Fildena CT®

fildena purple

Brand(s): Fildena CT

Manufacturer: Fortune Health Care

Generic name: Sildenafil Citrate

Formula: C28H38N6O11S

Pharmacologic Classifications: Type 5 Inhibitor

Fildena CT 100 / CT 50 Review

fildena ctFildena CT 100 belongs to the Fildena family of generic Sildenafil treatments manufactured by Fortune Healthcare in India. It contains 100 mg of Sildenafil Citrate, an active pharmaceutical ingredient (API) used in the treatment of Erectile Dysfunction (ED) in the male population.

Although there are actually a number of products under the Fildena line, Fildena CT is not an ordinary pill, as it takes a chewable form which is not the conventional oral delivery for Sildenafil products. But the product is beneficial and made for those patients having difficulties with the conventional hard pill types for easier delivery, mainly. Aside from these chewable tablets, Fildena also has oral gels, soft gel capsules, double strength pills, and others.

Erectile dysfunction affects a large number of the male population and treatments are continuously innovated to cater to the treatment needs of the population affected by ED. The dysfunction affects men of all social strata, so treatment also should be accessible to every patient. However, that notion is still far from ideal as ED treatment remains elusive for the masses, as the branded treatments are generally very costly. So, although still uncertified by the US FDA, companies continue to produce generic treatments for the patients.

About Fortune Healthcare

Fildena is a popular brand especially among patients online. As mentioned earlier, it is manufactured by Fortune Healthcare, a brand which is well-known for its products specially made for erectile dysfunction. Although the company has a lot of other products, it is known for producing the Fildena line of products for Sildenafil which involves a number of Sildenafil products in a number of variations and formulations like Fildena CT products, which are chewable Sildenafil tablet.

The company is native to India (Vadodara, Gujarat), and was established some 20 years ago (1986). Fortune Healthcare, aside from manufacturing pharmaceutical-grade products for ED, has also a number of other products for other medical conditions as well, like products for tuberculosis, bacterial infections, pet medicine, and herbal products. These products manufactured by the company take capsule, granule, ointment, tablet, and liquid oral forms.

Regarding the approvals, the company has its local Indian FDA approval (implied by its long run time) plus it has several accreditation from South East Asian countries like the Philippines. Fortune Healthcare has not been approved by the US FDA, though, but it has been accredited for one of its manufacturing facilities by the World Health Organization. Site information says that its manufacturing facilities were made to be GMP compliant, so it’s just a matter of waiting for the other facilities to get accredited too.

Since the company is majorly concerned with its product quality, it has dedicated a team for research and development to further develop and improve their existing products and to innovate and create new pharmaceutical formulations which will be effective in their applications in the medical field.

Research on Sildenafil Citrate

Although Sildenafil has proven itself effective in the management of erectile dysfunction in the male population, there are certain patients who need ED treatment but with a lot of contraindications for the drug, which limits their options for ED treatment. Also, some are unresponsive to Sildenafil due to other medical complications which meddle with the pharmacokinetics of the drug rendering it ineffective for some patients. The study “Combination therapy for erectile dysfunction: an update review” by Dhir et.al. in 2011 explored published literature on the existing combination therapies available for ED treatment which involves Sildenafil plus other treatment modalities [5]. The published results include PDE5 (phosphodiesterase type 5) inhibitors (treatments like Sildenafil) plus vacuum erection device (VED), intracavernous injection (ICI), intraurethral vasoactive prostanoids (intraurethral medication), α-blockers, androgen supplements, and many others. The review of the literature concerning PDE5 was positive towards the use of PDE5i plus conjunctive treatments as they were found effective in treating recalcitrant/unresponsive ED cases, and that there is a positive implication on the future ED treatments. But the researchers recommended that further studies and testing should be done as there are a lot of limitations to the current combination treatments.

There are some cases when ED in patients is only secondary to a dominant disease or injury, for instance, spinal cord injury (SCI). Patients with SCI are also diagnosed with ED as a consequence of the disease, so the effectiveness of PDE5is was also studied for the treatment of ED in SCI cases. The study, “Efficacy and satisfaction rates of oral PDE5is in the treatment of erectile dysfunction secondary to spinal cord injury: A review of literature” by Rizio et.al. studied the effect of the PDE5 treatments for ED in patients with SCI. The authors studied the effect of Sildenafil, Vardenafil, and Tadalafil in ED, and all the three mentioned PDE5i meds are able to help the patients regain their lost erectile function, but among all of them, Tadalafil had the longest effect on erectile function in the patients. Aside from that, though, there was no significant difference in the measure of satisfaction that these 3 products impose on the patients with SCI-induced ED.

Since PDE5is like Sildenafil are proven to treat ED in patients, its treatment cost is also studied in comparison with other existing treatment modalities like papaverine-phentolamine injections. The study “Cost-utility analysis of sildenafil compared with papaverine-phentolamine injections” by Stolk et.al. studied the cost-effectiveness of Sildenafil vs phentolamine injections in several respondents (169) residing in Rotterdam. The researchers found out that treatment with Sildenafil is cost-effective compared with phentolamine injections as measured using the clinical outcomes into quality-adjusted life years (QALYs).

The Function of Sildenafil

The mechanism of Sildenafil lies within its PDE5-inhibiting characteristic. PDE5 inhibitors are known to suppress PDE5 from degrading cGMP (cyclic guanosine monophosphate). cGMP is the one responsible for encouraging vasodilation and blood flow into the penile corpus cavernosum, therefore mediating erection. Since cGMP levels are maintained the erectile response is enhanced and maintained for a few hours, as long as Sildenafil is still in effect.

Effects of Sildenafil Citrate

Sildenafil can be expected to function as described, as Sildenafil effectiveness is already established. Using Sildenafil helps patients regain their erectile function, even if the ED is caused by various reasons or underlying diseases. Since its discovery, Sildenafil has already been effective in the treatment of ED in most cases, as there are only a few medical conditions that intervene with the effectiveness of the drug. But overall, Sildenafil can be expected to work most of the time.

Fildena CT 100 can also be expected to function like the brand-name medications since they have the same active pharmaceutical ingredient (API). Fildena CT 100 also contains 100 mg of Sildenafil, which is an effective dose of Sildenafil typically recommended by assessing physicians (“Sildenafil” by Langtry et.al. in 1999).

Recommended Doses and Duration of Therapy

Patients are usually prescribed with 50 mg of Sildenafil and doctors advise patients to take the medication at least an hour before the sexual activity. According to Langtry [8], patients may be recommended to take 100 mg of the drug depending on their tolerance for the drug [8]. Also, there are studies recommending higher doses of up to 200 mg for the treatment of ED in patients, depending on the patients’ cases.

Side effects and Warnings

In the study by Rizio et.al, the respondents were seen to have side effects of mild hypotension, flushing, and headache with the use of PDE5is like Sildenafil. These side effects are actually common in Sildenafil users, and these side effects are just transient in nature and are manageable.

There are other side effects, though, which are not common, like tachycardia, nausea, vomiting, dizziness, vision changes, tinnitus, and a number of others. Side effects should go away on their own when the medication is metabolized in the bloodstream, so when these side effects are prolonged, they patients should be concerned and seek medical help immediately.

Drug Interactions

Drugs contraindicated with Sildenafil are Flomax, Provigil, and grapefruit juice. Nitrates for blood pressure and cardiovascular diseases are highly contraindicated, as they may cause blood pressure crisis. There are also a number of products which are potentially toxic when taken with Sildenafil like Diflucan, Crixivan, Tykerb, Mifeprex, Viracept, Ketek, Reyataz, and others. Drugs which are contraindicated for Sildenafil involve a long list, so patients should check with their GP regarding the drugs they can safely continue to take along with Sildenafil.

Customer Reviews

There are many client comments about Fildena CT 100 as they found the product effective in treating ED. Aside from that, there are comments about its being chewable, which helped patients to enjoy taking the drug. Cheapgenericeddrug.com reviewers like James and Richard appreciated the fact that Fildena CT 100 comes in chewable form. Not only were they pleased with the product’s flavor, but they also were amazed at how the drug worked properly as well.

Thefildena.com reviewers were also happy with the outcome of their Fildena CT 100 intake, and the buyers who commented on the site were thoroughly pleased with the drug being in chewable, easy to process oral form. Mark and Kent, who were buyers from the site were very pleased with the result of their Fildena CT 100 use, and their good comments about the product reflect how glad they were.

There are only a few companies which manufacture other forms of Sildenafil products for their patients like the chewable ones. But it seems that the chewable form is quite popular with those who were able to try the product, so it is generally recommendable for those with ED but are having trouble in taking the regular medication form.

Fildena CT 100 Price, Available Forms, and Dosage

Although FIldena CT 100 is in an unconventional form (in chewable form), there is nothing special in its price as buyers can still have them at a cheaper cost. The product’s price did not vary much from the regular 100 mg hard pills. They have similar prices, so the clients may choose Fildena CT 100 over the regular pill only because of its chewable form, and not really the price. Fildena chewable tablets are sold for $3.20 each, but the prices get lower when patient buy more.

Shipping rates across sites are almost the same, as they are charging a minimum of $10 the regular shipping fee. Some stores, though, can charge for free, but it is noticeable that they are just passing on the shipping costs to the buyers by having higher product prices. In this shop’s case (fildena.bz) though, the shipping rate is set at a minimum of $10. The rates are uniform regardless of the destinations.

Buyers from the USA, Canada, Australia, Europe, the UK, and Asian countries are catered to by online pharmacies, as there are only a few which have restrictions with regards to shipping. Since there is uniformity when it comes to shipping charges, buyers can expect the same shipping rate (per courier) for any destination in any part of the world.

Conclusion and Rating

Fildena CT 50 is one of the products made by Fortune Healthcare (India) containing Sildenafil; the company actually has several products named Fildena, but there are variations to them. In Fildena CT 100’s case, the product is in chewable form, which made it enjoyable to take by the patients under Sildenafil treatment.

As for the product reviews, it is notable that the patients were happy about their Fildena CT 100 purchases, as they not only found the product effective in treating ED; they also found the chewable tablet rather easy and fun to take. It seems that the chewable form treatment for ED is well-tolerated and popular among those who were able to try it.

Overall, I think Fildena CT 100 is highly recommendable, as it was not only found effective for ED treatment, but it also eliminated the difficulty during intake the other patients had with the regular hard pills. Also, the product being in the chewable/orodispersible form made it a bit faster to absorb and to take effect. 4 out of 5 is my rating for the drug, and I recommend the product to be tried by those who are under ED treatment who are having difficulty in taking their regular hard pill medication.

Fildena CT 100 Wiki Facts

Brand: Fildena CT 100

Active Ingredient: Sildenafil Citrate

Treatment: Erectile Dysfunction

Manufacturer: Fortune Healthcare

Country of Manufacture: India

Availability: UK, USA, EU, India, South East Asia +

Reference List

  1. Fildena CT 50 mg Chewable (Soft Tabs). Available from: http://www.comfortcareco.com/fildena-ct-50.html.
  2. Chen LL, Pfister WR, Renn DW, Buranachokpaisan T, Osborne J, Tan HS, Tao L, inventors; Lavipharm Laboratories Inc., assignee. Compositions and methods for mucosal delivery. United States patent US 6,552,024. 2003 Apr 22. Available from:https://www.google.com/patents/US6552024
  3. Fildena CT 100. Available from: http://fildena.bz/fildena-ct-100.html
  4. Profile. Available from: http://www.indiamart.com/centurionpharmacy/profile.html#
  5. Dhir RR, Lin HC, Canfield SE, Wang R. Combination therapy for erectile dysfunction: an update. Asian journal of andrology. 2011;13:382-90. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739353/
  6. Rizio N, Tran C, Sorenson M. Efficacy and satisfaction rates of oral PDE5is in the treatment of erectile dysfunction secondary to spinal cord injury: a review of literature. The journal of spinal cord medicine. 2012 Jul 1;35(4):219-28. Available from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425878/
  7. Stolk EA, Busschbach JJ, Caffa M, Meuleman EJ, Rutten FF. Cost utility analysis of sildenafil compared with papaverine-phentolamine injections. Bmj. 2000 Apr 29;320(7243):1165. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27357/
  8. Langtry HD, Markham A. Sildenafil. Drugs. 1999 Jun 1;57(6):967-89. Available from: http://link.springer.com/article/10.2165/00003495-199957060-00015
  9. Edwards J. List of 56 Drugs That Should Not Be Mixed With Viagra Contains Some Surprises. Available from: http://www.cbsnews.com/news/list-of-56-drugs-that-should-not-be-mixed-with-viagra-contains-some-surprises/